Pregnancy

Overview

Many individuals with ichthyosis have healthy pregnancies and babies. However, pregnancy can bring  unique challenges depending on your specific type of ichthyosis, the medications you use, and how  your skin responds to hormonal and physical changes.

This guide provides general information and helpful questions to discuss with your healthcare team  before, during, and after pregnancy.

Before Pregnancy

• Meet with your dermatologist and obstetrician (OB-GYN) before becoming pregnant. They can help  you review medications and develop a care plan.
• Genetic counseling is recommended if you or your partner have ichthyosis or a family history of the  condition. A genetic counselor can explain inheritance patterns, carrier testing, and prenatal testing  options.
• Medication review: Some common treatments for ichthyosis—especially oral retinoids like acitretin or  isotretinoin—can cause birth defects and must be stopped well before conception. Discuss safe  alternatives with your dermatologist. 

During Pregnancy

• Hormonal changes may make your skin drier or oilier, and scaling may increase or decrease.  
• Some people experience itching, cracking, or increased irritation as their abdomen stretches.  
• Use gentle, fragrance-free moisturizers multiple times per day. Ointments or creams with petrolatum,  ceramides, or urea can help maintain skin hydration.  
• Avoid overheating, which can worsen itching or irritation.  
• Monitoring and Care  
  • Tell your OB team about your skin condition early. They can help coordinate care with a  dermatologist familiar with ichthyosis.  • Hydration and nutrition are especially important—drink water regularly and follow a balanced diet.  • Infection prevention: If skin cracks or fissures appear, monitor for redness, swelling, or pain, and  contact your provider if infection is suspected.

Labor and Delivery

• Let your birth team know about ichthyosis before delivery.  
• Some individuals with thicker scaling or limited flexibility may prefer certain positions for comfort.  
• If you have collodion membrane at birth or a severe type of ichthyosis, inform your newborn care  team so they can monitor your baby’s skin closely.  
• A neonatologist or pediatric dermatologist may be consulted for your newborn if ichthyosis is  suspected.

After Pregnancy

• Hormonal changes can affect your skin in the months after delivery—keep your regular moisturizing  routine and monitor for flares.  
• Sleep deprivation and stress may worsen symptoms; ask for support from family, friends, or your  healthcare team.  
• Most moisturizers are safe to use while breastfeeding, but avoid applying products with salicylic acid, urea (>10%), or retinoids on areas where your baby’s skin may come into contact.
• If you need medication, confirm safety with your OB or pediatrician.

Genetics and Inheritance

• Ichthyosis can be inherited in several different ways (autosomal dominant, autosomal recessive, or X linked).  
• A genetic counselor can help explain your family’s specific pattern and what it means for future  pregnancies. 

Emotional Well-Being

• Pregnancy and parenting with ichthyosis can be rewarding and challenging.  
• Peer support through FIRST’s Peer Navigator Program and online communities can connect you with  others who’ve had similar experiences.

When to Contact Your Doctor

• Sudden worsening of skin symptoms  
• Signs of infection (pain, pus, fever, swelling)  
• Concerns about medication safety or side effects  
• Questions about genetic risks or testing options 

Helpful Resources

Genetic Counseling Resources  
www.nsgc.org – National Society of Genetic Counselors  
Pregnancy Exposure Information  
www.mothertobaby.org – Medication safety during pregnancy & breastfeeding

Download the Pregnancy & Ichthyosis PDF

FIRST Member Jordan Flake shares her tips for handling pregnancy with ichthyosis.